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It does not require injections, has no fasting or food restrictions, and does not use the SNAC absorption enhancer needed by oral semaglutide (Rybelsus)

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As of 2025, tirzepatide (Zepbound) is FDA-approved for moderate to severe obstructive sleep apnea in adults with obesity, making it the first medication approved for this indication

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Avoid eating within three hours of bedtime, as lying down with a full stomach exacerbates delayed gastric emptying

Semaglutide is generally well-tolerated in patients with arthritis, though common side effects like nausea or constipation may occur