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Second, the respective study populations were quite different, with STEP 1 including a younger, healthier population with more women (73.1% of the semaglutide arm in STEP 1 versus 27.7% in SELECT) and higher mean BMI (37.8 kg m 2 versus 33.3 kg m 2 , respectively) 14,21
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and Metabolism 91 (5), 19161923

40 , 54 In adults with overweight or obesity at high cardiovascular disease risk (without diabetes), liraglutide 3.0 mg plus lifestyle intervention lowered visceral adipose tissue over 40 weeks compared to placebo (12.5% vs
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Malik, V
