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Big news: The World Health Organization (WHO) has released its first global guideline on using GLP-1based medicines to treat obesity redefining obesity as a chronic, relapsing disease that deserves long-term care

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Among ASCVD patients, 79,516 individuals (34.63% of ASCVD patients) also suffered from type 2 diabetes mellitus and 15,624 individuals were diagnosed with obesity

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GLP-1 receptor expression in intima and media was lower in obesity group compared to non-obesity group which was correlated with the alteration of TCF7L2 expression