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The Safety, Tolerability and Efficacy of Rapid UpTitration of GuidelineDirected Medical Therapies in Acute Heart Failure (STRONG-HF) trial validated rapid up-titration strategies, demonstrating that early high-intensity GDMT implementation with structured follow-up significantly reduces 180-day mortality and readmissions

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And, since cardiovascular diseases are our leading killers, it also makes sense that excess intake of ultra-processed foods could lead to increased overall mortality