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Recent randomized controlled trials show that combining GLP-1RAs with exercise yields additive benefits, including greater reductions in metabolic syndrome severity, abdominal obesity, oxidative stress and inflammation, and improved weight loss maintenance after cessation of pharmacotherapy (16, 17, 19, 21)

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Patients taking semaglutide should contact their healthcare provider promptly if they experience sustained blood pressure elevations

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If you're also taking insulin or sulfonylureas, be aware of increased hypoglycemia risk and discuss potential dose adjustments of these medications

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Collecting and analyzing real-world data from their patients, then, will be top of mind for these companies next year

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It is also worth noting that hiccups can occur as part of a broader constellation of upper gastrointestinal symptoms, particularly during dose escalation phases when the body is adjusting to the medication

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