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A video was also provided in Obesity Matters input
doi: 10.1185/030079908X253870

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Lancet 2021;397: 17361748
Patients should be advised to increase activity levels gradually and consider professional guidance from physiotherapists or exercise specialists

When overweight or obese individuals lose significant weight, their hormonal balance often shifts favourably: insulin sensitivity improves, androgen levels may normalise in women with PCOS, and inflammatory markers decrease