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Miners JS, Barua N, Kehoe PG, Gill S, Love S
10.1016/j.biopha.2020.110523 47 LillyE

The most common adverse effects are gastrointestinal , occurring in 20-50% of patients and including nausea, vomiting, diarrhea, constipation, and abdominal pain

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Multiple head-to-head trials demonstrate 15-20% body weight reduction with tirzepatide at therapeutic doses versus 10-15% with semaglutide

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