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It is estimated that clinical trials evaluating liver-related events in patients with MASLD and compensated or decompensated cirrhosis would require a minimum recruitment of 2,886 patients with at least four years of follow-up and 1,602 patients with at least two years of follow-up, respectively

Pitt B, Filippatos G, Agarwal R et al (2021) Cardiovascular events with finerenone in kidney disease and type 2 diabetes

Your risk is higher if you: Already have GERD or frequent heartburn Are very overweight (extra belly fat pushes on your stomach) Eat large meals or foods that trigger reflux Lie down soon after eating Have a hiatal hernia or other digestive problems How to Manage Acid Reflux While Taking Semaglutide You dont have to stop your medicine if you get heartburn