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Description
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preliminary data is promising
The GLP-1 receptor pathway involves GLP-1 binding to its receptor (GLP-1R), which activates G-proteins, leading to increased cyclic adenosine monophosphate (cAMP) levels and subsequent activation of protein kinase A (PKA)

Diabetologia 54, 965978

10.1016/j.reprotox.2008.05.064 [DOI] [PubMed] [Google Scholar] 21
Whilst GLP-1 receptor agonists themselves have a low risk of causing hypoglycaemia, blood glucose fluctuations may occur, particularly when these medications are combined with insulin or sulfonylureas
