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In the Veterans Health Administration (VHA) national dataset, an adjusted OR indicated no significant difference in pancreatitis occurrences between thiazolidinedione and incretin groups (adjusted OR, 0.94

Obes Surg 34(2):303309 Vinciguerra F et al (2023) High-dose liraglutide improves metabolic syndrome in poor responders to bariatric surgery

This analytical review critically examines the evidence surrounding GLP-1 agonists efficacy, safety, and real-world implications for obesity treatment in individuals without diabetes

A fatty acid is attached to the lysine at position 20, increasing affinity for endogenous albumin, thereby extending its half-life and allowing for sustained therapeutic effects

GLP-1 receptors are found in key brain regions, such as the ventral tegmental area and the nucleus accumbens, which are central to the mesolimbic dopamine system

After administration of Triple GLP-1/GIP/glucagon receptor agonist, learning and memory impairment of AD models (APP/PS1 mice and 3Tg-AD mice) was improved, amyloid plaques, tau pathology, inflammation response and oxidative stress in brains of two AD models were ameliorated (239241)