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For now, the tension between innovation and compliance remains a defining feature of the GLP-1 landscape

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Learn about the results, how it works, when it will be available in the US, and more.

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Again, every person and situation is different

In most major obesity trials, GLP-1 therapy was: Escalated to high or maximum tolerated doses Stopped abruptly, not down-titrated Followed by little or no continuation of structured lifestyle support In the STEP-1 extension trial (semaglutide 2.4 mg), participants who discontinued therapy regained approximately two-thirds of their prior weight loss over the following year