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The responder rates are more decision-useful than the mean: Tirzepatide roughly doubled the odds of hitting the 25% threshold and nearly tripled them at 30%

Not all applicants will be approved - the prescribing decision rests entirely with the independent clinician

New England Journal of Medicine 384:9891002

As of the time of writing, retatrutide has not been granted a marketing authorisation by the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA)

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Kristensen SL, Rorth R, Jhund PS, Docherty KF, Sattar N, Preiss D, et al