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Earlier use of pharmacotherapy is encouraged Medications should be considered early, especially in patients withor at high risk ofobesity-related complications

This newly charted pathway - separate from previously described mechanisms that broadly affect appetite - could be an avenue by which GLP-1s treat other dysfunctions in reward processing, such as substance use disorder

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Insufficient stomach acid, an unbalanced microbiome, and aging can lead to low enzymatic production and increased digestive issues

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