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Participants receiving efpeglenatide more frequently achieved weight loss of 5% or 10%

Taken altogether, these mechanisms explain the clinical use of GLP-1RAs as beneficial treatment options for T2DM and obesity

Temporal impact of treatment duration on tumor risk The duration of treatment with GLP-1RAs is a critical factor influencing clinical outcomes

Benefits of Saxenda Weight loss when on Saxenda varies, often depending on the dose

DOI: 10.1038/s44360-026-00108-y The authors report no outside funding

In contrast, self-pay obesity patients will prioritise the higher efficacy of injectables over the convenience of oral pills