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Differences in efficacy among GLP-1 RAs belonging to the same class seem less significant

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Additionally, the phase 2 MOMENTUM clinical trial of pemvidutide (a dual GLP-1/GCG agonist) showed that only 21.9% of WL was attributable to reductions in lean mass at 48 weeks (overall WL 10.315.6% across doses) [64]

Patients who were prescribed GLP-1 drugs had a 40% lower rate of opioid overdoses and a 50% lower rate of alcohol intoxication compared to those not taking these medications

Some of the buzzier side effects, such as Ozempic face or Ozempic butt, are not caused by any interaction with the drug but instead are unintended weight loss consequences

According to NHS guidance, neurological symptoms can occur even without anaemia, and the severity of symptoms does not always correlate with B12 levels