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Description
10,117119 This is partially due to limited overlapped distribution of the GLP-1 with GLP-1R neurons in the NTS, but with the terminals of vagal afferents from the gastrointestinal tract

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That is significantly more than the roughly 15% achieved with semaglutide at its highest dose in comparable trials

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Therefore, immune checkpoint inhibitors (ICIs) can be used to treat BCG non-responsive bladder cancer patients, but the overall response rate of bladder cancer patients to PD-L1/PD-1 blocking drugs is about 20-30%
