semaglutide results reddit My thoughts after 12 months on Wegovy (and a weight loss of 88 lbs) : r/ Before and after pics. :

Weeks 2 to 4: Measurable Appetite Change and Early Weight Shifts By week two, appetite suppression becomes consistent and noticeable

They did note a mild rise in gallstone disease (OR 1.30, p = 0.041)

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Its also worth noting that reaching the maintenance dose, which usually happens around 17 weeks, is when many people see the most substantial changes

doi: 10.1007/s00418-015-1333-3 53 KorneliusETsouSHChangCCHoYJLinSCChenWLet al

For oral semaglutide, the empty-stomach requirement is non-negotiable for absorption