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However, unlike the relatively predictable conversion from MCI to AD, the progression from hyposmia or rapid eye movement sleep behavior disorder to PD is variable [107], complicating the assessment of GLP-1RAs efficacy in preventing phenotype conversion
That being said, there is no significant clinical evidence to support its long-term safety, nor is it FDA-approved
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DPP-4 degrades GLP-1, leading to the formation of biologically inactive metabolites [10]
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