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10.2337/db09-9028 181

Adequate sleep and recovery allow that preservation to actually happen

, Burn, P

Additionally, proteolytic degradation is a major challenge in peptide-based therapeutics, as it results in short half-life, low bioavailability, rapid clearance, and ultimately reduced therapeutic efficacy

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Therefore, we have heated the mimic MNs formulation and control samples (using PBS as a diluent) at extremely high temperature (80 C for 1h)