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There are also emerging geographic and demographic disparities: studies have found lower GLP-1 fill rates among patients with obesity (37% fill rate) versus those with diabetes (4765% fill) ( [30] ), and lower fill rates for Hispanic and Black patients, reflecting both socioeconomic and coverage gaps ( [31] )

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Common adverse effects associated with Ozempic include gastrointestinal symptoms such as nausea, vomiting, diarrhoea, and constipation, particularly during the initial titration phase

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[55] More significantly, it influences fat metabolism by promoting the "browning" of energy-storing white adipose tissue into energy-burning brown adipose tissue (BAT)

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Zaibi MS, Stocker CJ, ODowd J, Davies A, Bellahcene M, Cawthorne MA, et al

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8 Generally, these side-effects are self-limited, occur more commonly shortly after drug initiation or during dose escalation periods, and lessen after a few weeks of GLP-1 RA administration

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