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Conclusions GLP-1 agonists are associated with significant pancreatitis risk which increases with larger cumulative doses.

By Sabina Paglialunga, PhD & Aernout van Haarst, PhD Senior Directors Scientific Affairs Glucagon-Like Peptide-1 (GLP-1) receptor agonists first came to the market in 2005 as a type 2 diabetes mellitus treatment, and they have been making headlines again for their weight reduction effects

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GLP-1 drugs like Ozempic have transformed weight management, but concerns around muscle loss, bone density, dampened desire, and dependency are growing