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Brazil records 28.9% growth, reflecting rapid expansion of private insurance coverage and growing physician adoption of obesity pharmacotherapy

Large-scale clinical trials tracking once-weekly therapies show that symptoms are typically mild-to-moderate, temporary, and highly dose-dependent

These molecules penetrate the intestinal mucus layer to directly interact with epithelial and immune cell receptors, thereby modulating host signaling pathways to maintain redox homeostasis [75]

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An enzyme called dipeptidyl peptidase-4 (DPP-4) rapidly metabolizes GLP-1 and GIP, rendering them inactive

Exclusion criteria and differential diagnosis