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The author concludes that prophylactic use of PPIs must be carefully considered and may not be worth the risk

FXR, farnesoid X receptor

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Some are used for type 2 diabetes
A newer version of phentermine (combining phentermine with topiramate in one pill) was approved for chronic weight management in adults and kids down to age 12 in 2012 and marketed as Qsymia

313 High expression of claudin-2, a tight junction protein, can increase the permeability of the intestinal barrier and disrupt its structure
