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When retatrutide does become available, we suspect the guidance will be the same low and slow approach to upping doses

Conclusion: Embarking on a medical weight loss journey with GLP-1 therapies involves navigating various aspects, and constipation is one consideration that shouldn't be overlooked

The mechanism(s) by which GLP-1RAs would cause NAION is also unclear, particularly as GLP-1RAs are associated with neuroprotective properties and reductions in ischemic risk (96), but it has been hypothesized to be related, like the exacerbation of retinopathy, to rapid improvements in glycemic control (Figure 3)

Understanding the potential digestive symptoms can help patients and healthcare professionals implement appropriate management strategies and set realistic expectations for treatment tolerance

Nettelbladt, C

The postprandial studies mainly showed significant or marginally [15] significant results both in patients with type 2 DM and healthy subjects [15,17,18]