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This could worsen inflammation or introduce bacteria

Martin Whyte, an associate professor of metabolic medicine at the University of Surrey, explains one possible theory as to why people tend to regain weight after they stop these medications

To learn more about how semaglutide works for weight loss, explore our blog today

Apr 29, 2026 Articles, Diabetes, GLP- 1 Agonist Therapy Center, GLP-1 Agonist Therapy Center, Therapies, Type 2 Diabetes, Type 2 Diabetes 1,040 views The rise of oral GLP-1 medications is changing how clinicians approach type 2 diabetes treatment

This effect was mediated via adenylate cyclase (AC) / PKA signaling pathway, as it was abolished by the GLP-1R inhibitor exendin-9, or by PKA inhibitors SQ22536 and H89 [58]

Decisions about continuing or stopping treatment should be made with a healthcare provider, considering: Weight loss progress Side effects experienced Personal health goals Other medical conditions Alternatives and Complementary Strategies While GLP-1 agonists can be powerful tools, they are not the only option for weight loss