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Food intake Singly housed, overnight-fasted mice were given metformin or vehicle orally 1 h prior to re-feeding and food weight was recorded at the indicated time-points

l-valine and d-glucose group, n = 6

GLP-1 (Glucagon-Like Peptide-1) Receptor Agonism GLP-1 is an incretin hormone secreted by intestinal L-cells in response to food intake

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