half life of glp 1 agonists Structure and half-lives native human GLP-1, liraglutide and Generation of novel long-acting GLP-1R
Description
Weekly injections do not appeal to every patient
However, tolerability, discontinuation rates, and comparative efficacy will be key watchpoints
Many peptide drugs require daily injections, which may affect their tolerance and patient compliance
Similar evidence has been obtained in non-diabetic male mice 50 and rats 51
This is the first study of its type looking at longer-term maintenance with an oral GLP-1 after taking an injectable, said Dr
doi: 10.1016/j.kint.2019.09.013
