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We dont see enough about resiliency

Among its findings: Protandim increased the median lifespan of male mice by 7% which the paper characterized as a small but statistically significant change that wasnt seen in female mice
GLP-1 agonism has been attributed to maintaining dopamine homeostasis, but current research suggests GLP-1 agonism more accurately reduces dopamine signaling in the mesolimbic system regardless of the current state of the system [158]

2012;7(2):e32008

1d) and then compared to in vivo exposure levels

Nausea, which affected 18-36% of participants at the 4 mg dose and 17-60% at the 8 mg dose in clinical trials, usually peaks during the first week of each new dose level and then subsides as the body adapts