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New data from 333,000 patients: 3 years on: 18% risk of heart attack, stroke, death Stop at 12 months: +14% risk Stop at 18 months: benefit fully erased Stop at 24 months: +22% risk It takes 3 years to build it

In the recent SOUL trial, the GLP-1 drug reduced the risk of MACE by 14% over 4 years