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Wegovy (semaglutide 2.4 mg) ~15% mean weight loss at ~68 weeks Strongest CV outcomes and long-term safety base Still a blockbuster but clearly behind on magnitude

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The effect of tirzepatide on appetite was less pronounced in the group that had used semaglutide before the switch compared with the group that had used dulaglutide

Professor Arnold G Vulto, PharmD, PhD, FCP Abstract: Kinase inhibitors form the largest class of novel anticancer drugs