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The legislative outcome will define the commercial calculus for drugs entering development today, given typical 10-12 year development timelines

Watch for amplified gastrointestinal symptoms (nausea, vomiting, constipation), increased drowsiness or dizziness, impaired coordination, and any mood changes

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PRECIDENTD is an ongoing, pragmatic randomised trial that will directly compare GLP-1 receptor agonists with SGLT-2 inhibitors for CVD and kidney events (NCT05390892)

These are key statistics from one double-blind trial on 1,961 adults who received a once-weekly injection of semaglutide at a dose of 2.4 mg for 68 weeks