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Obesity as a correlate of outcome in patients with bipolar I disorder

The quality of available evidence is further limited by methodological concerns, including small sample sizes, short study durations, lack of standardisation in probiotic formulations, and potential publication bias favouring positive results

Lee N, Kim Y

Overall, the authors conclude that: The recognition that several gastrointestinal hormones, released in response to nutritional stimuli are important regulators of appetite (PYY, oxyntomodulin, GLP-1 and decreased secretion of ghrelin), offers a strategy for the development of more effective ant-iobesity agents.treatment of obesity could involved a combination of hormones, e.g

Researchers who maintain a consistent exercise routine while on retatrutide often see their resting heart rate stabilize or even decrease below baseline over months, despite the pharmacological effect pushing it upward