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"Efficacy and tolerability of tirzepatide, a dual glucose-dependent insulinotropic peptide and glucagon-like peptide-1 receptor agonist in patients with type 2 diabetes: A 12-week, randomized, double-blind, placebo-controlled study to evaluate different dose-escalation regimens"

Maack C, Lehrke M, Backs J, Heinzel FR, Hulot JS, Marx N, Paulus WJ, Rossignol P, Taegtmeyer H, Bauersachs J, et al

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U pacjentw ze wskanikiem masy ciaa ( Body mass index BMI) powyej 35

Long-Term Safety Questions While short-term safety data for tirzepatide is reassuring, the long-term implications of dual agonism remain incompletely understood