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Imbalance toward GIP receptor, combined with distinct signaling properties at the GLP-1 receptor, together may account for the promising efficacy of this investigational agent

However, these effects are usually mild and tend to improve over time

Some people plateau on one and switch

Klein also suggests avoiding common acid reflux triggers like: Onions Alcohol Chocolate Citrus fruits Spicy foods Peppermint Tomato sauce Fatigue Fatigue is a less common side effect of Ozempic, but some people may experience tiredness when they first start the medication or when they move to higher dose strengths

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