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Evaluation of the Incretin Effect in Humans Using GIP and GLP-1 Receptor Antagonists

Managing Common Side Effects During Treatment Nausea is the most frequently reported side effect during the first 2-3 weeks, affecting approximately 25-40% of users, but typically improves as your body adjusts

Its normal for it to slow and fluctuate between dose increases, then pick up again once the next increase takes effect and the body adapts to a new set point (a lower body fat level)

Women may find that they achieve satisfactory appetite control and weight loss at doses that would be considered sub-therapeutic for men

Never attempt to refreeze a thawed injection, as this significantly increases degradation risk

Diabetes Care, 43:2859-2869