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Noteworthy, neither PRA nor plasma aldosterone significantly changed after six months of treatment, confirming the transient diuretic effect of SGLT2-i

GLP-1Rs are also found in circumventricular organs (CVO), the hind brain, and the thalamus

Studies involving animal subjects

At this stage we believe we achieved these unique properties with two amazing molecules one with the QW (once-a-week) dosing and another with QD (once-a-day) dosing and exceptional safety profile based on the currently available data

This flattens postprandial glucose spikes and help control blood sugar

In terms of side effects and tolerability, the advantage goes to Amycretin