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Thus far, the effect of tirzepatide on cardiovascular risk factors has indicated improvements in lipids, lipoprotein profiles, glucose control, body weight, blood pressure, and several biomarkers of inflammation in adults with overweight or obesity both with and without T2D (Tables 1, 2, 3, 4)

Abbreviations AEs: Adverse events NAEs: Neurological adverse events FDA: The Food and Drug Administration FAERS: The FDA Adverse Event Reporting System GLP-1 RAs: Glucagon-like peptide-1 receptor agonists ADRs: Adverse drug reactions PTs: Preferred Terms SOCs: System Organ Classes IQR: Interquartile range ROR: Reporting odds ratio CI: Confidence interval PRR: Proportional reporting ratio BCPNN: Bayesian Confidence Propagation Neural Network EBGM: Empirical Bayesian geometric mean EBGM05: The lower limit of 95% CI of EBGM IC: Information component IC025: The lower limit of 95% CI of the IC VANs: Vagal afferent neurons T2DM: Type 2 diabetes mellitus OR: Odds ratios References Targher, G., Mantovani, A

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Semaglutide for Non-Alcoholic Fatty Liver Disease: Brand Names and Efficacy Non-alcoholic fatty liver disease (NAFLD) is a common condition that is characterized by the accumulation of fat in the liver

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