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This limits our ability to determine whether diabetes itself constitutes an independent risk factor for adverse gastrointestinal outcomes with these agents

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All research doses (5mg, 10mg, 15mg) must adhere to these principles to ensure safe, reliable, and reproducible outcomes

Symptoms associated with serotonin syndrome may include the following combination of signs and symptoms: mental status changes (eg, agitation, hallucinations, delirium, and coma), autonomic instability (eg, tachycardia, labile blood pressure, dizziness, diaphoresis, flushing, and hyperthermia), neuromuscular symptoms (eg, tremor, rigidity, myoclonus, hyperreflexia, and incoordination), seizures, and/or gastrointestinal symptoms (eg, nausea, vomiting, diarrhea)