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Indeed, GLP-1RAs have evolved over time such that the frequency of dosing has decreased from twice-daily (exenatide, BD) [65], to once-daily (liraglutide, lixisenatide) [66, 67] to once-weekly (dulaglutide, exenatide QW, semaglutide) [5, 6], suggesting a higher adherence potential for the longer-acting agents (Table 2)

In contrast with DPP-4 inhibitors, GLP-1RAs have attracted attention because a weight loss effect appears when the dose of this drug is increased [23]

[CrossRef] [PubMed] [Google Scholar] Role of diabetes and its metabolic pathways in epilepsy: An insight to various target approaches In: Naunyn-schmiedeberg's archives of pharmacology

Declarations Ethics approval and consent to participate The study protocol received approval from the Institutional Review Board at the University of Florida, USA

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