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In addition to , and cells in the pancreas, the receptor has been found in a variety of other tissues, including the intestine, stomach, lungs, heart, kidneys and several regions of the central nervous system (Holst et al., 2019

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Initial preclinical results has been supported by encouraging data from intial clinical trials, which has given rise to further clinical evaluations

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Vagal stimulation and prevention of sudden death in conscious dogs with a healed myocardial infarction

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