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Additionally, the nausea and vomiting associated with Ozempic can, in rare instances, be severe

Elimination is primarily renal, with no dose adjustment required for mild to moderate renal impairment

This dual approval underscores its powerful effects on both blood sugar control and weight

Compared with lixisenatide, exenatide twice daily, liraglutide, albiglutide and dulaglutide, semaglutide is associated with highest nausea and vomiting rates, yet also with highest rates of improvement in glycemic control and weight loss (132)

MASH (metabolic dysfunctionassociated steatohepatitis): Currently under FDA accelerated approval, pending confirmatory trial results

10.1002/hep.26093 194 ZisisM.ChondrogianniM