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It helps manage blood sugar by triggering insulin release and reducing glucagon

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This finding may have been due to enhanced early detection

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Effectiveness Both medicines have been shown in clinical trials to be highly effective at helping people lose weight, with Mounjaro (tirzepatide) helping people lose 22.5% of their starting weight on average, and Ozempic/Wegovy (semaglutide) helping people lose around 21% of starting weight

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Liraglutide as Adjunct to Insulin Treatment in Patients with Type 1 Diabetes: A Systematic Review and Meta-analysis

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Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of medicines primarily used to manage type 2 diabetes mellitus and, more recently, obesity

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However, in recent years, it has been increasingly recognised as a disease involving significant synovial inflammation (synovitis) [82,83]

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