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Before ISSA, I thought I had to go plant-based and restrict everything, he said

Chronic and uncontrolled hypercortisolaemia profoundly affects the physiological functions of key metabolic organs, including the liver, muscles, adipose tissue, and pancreas (17, 24) ( Figure 1 )

Funding We work in this area has been supported by the National Health and Medical Research Council (NHMRC) of Australia (ID: APP1147333), the National Natural Science Foundation of China (NSFC, ID: 81870561), Royal Adelaide Hospital Research Foundation, and the University of Adelaide

The Food and Drug Administration has also approved Wegovy as a treatment for heart disease, and Ozempic as a treatment to reduce risks of chronic kidney disease

Clinical Trial Limitations Interpreting the clinical data for both compounds requires careful consideration of study limitations and methodological differences

This approach effectively interferes with the body's ability to store lipids, thereby aiding in weight loss [6]
