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Notably, these pooled analyses included limited patients treated with semaglutide or tirzepatide
A nationwide Danish retrospective cohort study indicated that GLP-1 RAs may offer protection against lower extremity amputations in patients with T2DM, compared to sulfonylureas [98]
Successful treatment of binge eating disorder with the GLP-1 agonist semaglutide: A retrospective cohort study
Results from a phase 1 trial have supported further clinical evaluation with a dose-dependent WL up to 14.5% with AMG133 compared to 1.5% with placebo by day 85 [59]
Clinical studies suggest that WEGOVY leads to greater weight loss, making it a strong competitor
If the results are neutral, the conversation becomes more nuanced
