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Retatrutide remains under clinical investigation and has not been approved by the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA) for use in the United Kingdom

Simultaneously, the state of calorie deficit itself creates a catabolic environment, where the body breaks down tissue to meet energy demands

AOD-9604 has undergone extensive preclinical and clinical research, including multiple Phase II human trials demonstrating its safety and efficacy for body composition improvement

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Gasoyan H, Tajeu G, Halpern MT, Sarwer DB