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While tirzepatide may indirectly benefit PCOS through weight reduction and improved insulin resistance, this is not an FDA-approved indication and specific studies in PCOS populations remain limited

While gastrointestinal symptoms (nausea, vomiting, diarrhea, constipation) affect many patients initially, severe or persistent symptoms may necessitate dose adjustment, temporary dose reduction, or consideration of alternative therapies

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Dehydration commonly produces symptoms including fatigue, headache, dizziness, muscle weakness, and general malaise, which patients may interpret as flu-like