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There was no significant difference observed for PVD (HR = 1.20, 95% CI = 0.901.60), and stroke (HR = 1.24, 95% CI = 0.931.66) MI (HR = 1.18, 95% CI = 0.841.66) or heart failure (HR = 1.08, 95% CI = 0.891.32) (Fig 3)