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Regarding mitochondrial dysfunction involved in AD pathophysiology, it includes disturbances in oxidative phosphorylation (OXPHOS), and impaired energy metabolism as well as excess generation of ROS, altered mitochondrial biogenesis, transport and dynamics (68)

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1,5 Healthy fats Monounsaturated and polyunsaturated fatty acids (MUFAs and PUFAs, respectively) enhance GLP-1 secretion through free fatty acid receptor and G-protein-coupled receptor signaling pathways, including GPR40, GPR119, and FFAR1/3

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8 When GLP-1 receptors are activated, they promote insulin release and decrease glucagon secretion in response to glucose levels