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Risk of suicidality with GLP-1 drugs

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(2008, Metabolism) showed berberine at 500mg three times daily for 13 weeks reduced HbA1c by about 2% in newly diagnosed type 2 diabetics

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Whether or not people can successfully de-escalate could be related in part to how they metabolize the drug and the length of that steady state, Pinto says

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"Based on our study, we recommend that guidelines be updated with the following precautions for GLP-1 RA users undergoing endoscopic procedures: continue therapy, follow a liquid-only diet the day prior, and adhere to standard pre-anaesthesia fasting," said lead author, Dr Brent Hiramoto, senior gastroenterology Fellow at Brigham and Women's Hospital

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Both work best when paired with sustainable habits

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The results support the U.S

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