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The criteria differ from those used for the general population and are meant to guide safe, costeffective use within Medicare

Biochim Biophys Acta (2013) 1832(4):52741

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Osteopenia or osteoporosis (low bone mass)

Additionally, agents capable of positively modulating more than one peptide hormone receptor simultaneously, such as tirzepatide or the recently characterised GL-0001 peptide, could offer an even more exciting avenue to help realise the potential of gut-derived hormones to treat bone disease

Since Ozempic is considered off-label for weight loss, Cigna wont offer coverage under this scenario
